Concepedia

Publication | Closed Access

Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease.

40

Citations

0

References

1995

Year

Hiroto Kuwabara, Paul Cumming, Yoshifumi Yasuhara, Gabriel C. Léger, Mark Guttman, Mirko Dikšić, Alan C. Evans, Albert Gjedde
PubMed

Abstract

The striatal blood-to-brain transport of FDOPA remained unchanged while the DDC activity was differentially reduced within the striatum in Parkinson's disease. We found the FDOPA uptake maps useful in identifying altered patterns of FDOPA metabolism common in Parkinson's disease.