An Antibody Against Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) Dampens Proinflammatory Cytokine Secretion by Lamina Propria Cells from Patients with IBD - Concepedia

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An Antibody Against Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) Dampens Proinflammatory Cytokine Secretion by Lamina Propria Cells from Patients with IBD

DOI Full Paper Access

30

Citations

22

References

2016

Year

Siggeir F. Brynjólfsson, Maria K. Magnusson, Philip Kong, Teis Jensen, Joseph L. Kuijper, Katarina Håkansson, Christine B. Read, Vibeke W. Stennicke, Henrik Sjövall, Mary Jo Wick

Inflammatory Bowel Diseases

Abstract

An anti-TREM-1 antibody can dampen secretion of proinflammatory cytokines in inflamed patients with elevated PGLYRP-1. Moreover, PGLYRP-1 + myeloperoxidase is a potential biomarker for predicting the effect of anti-TREM-1 therapy.

References

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