Isolation of Transmissible Gastroenteritis Virus from Lungs of Market-Weight Swine

N. R. Underdahl, C. A. Mebus, E. L. Stair, Marvin B. Rhodes, L D McGill, Μ. J. Twiehaus

American Journal of Veterinary Research · 1974 · 22 citations · 0 references

Concepts

Abstract

SUMMARY Transmissible gastroenteritis ( tge ) virus was isolated from lungs of market-weight swine which had gross pulmonary lesions similar to those associated with mycoplasmal pneumonia. The tge isolate was neutralized by anti- tge serum. Pulmonary tissue from infected pigs had positive fluorescence when stained with anti- tge conjugate. Coronavirus particles characteristic of tge were demonstrated in pulmonary and intestinal material by electron microscopy. Swine with chronic tge viral infections of the lungs could be the source of infection for susceptible herds or for infection of newborn pigs within a continuous farrowing operation.