Concepedia

Safety of recombinant human deoxyribonuclease as a rescue treatment for persistent atelectasis in newborns

Atiye Fedakâr, Cavit Aydoğdu, Ali Fedakar, Murat Uğurlucan, Semih Bolu, Marina Iskender

Annals of Saudi Medicine · 2012 · 29 citations · 16 references

DOIFull text

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Abstract

rhDNase treatment is a safe option and may be used as an effective method for the management of persistent atelectasis in newborns, which is resistant to other conventional treatment methods.

References

16

Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic Fibrosis

Henry J. Fuchs, Drucy Borowitz, David Høyrup Christiansen et al. · New England Journal of Medicine · 1994 · 1.5K citations · Full text

Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus

Andrew Durward, Vito Forte, Sam D. Shemie · Critical Care Medicine · 2000 · 263 citations

Efficacy of Recombinant Human Deoxyribonuclease I in the Hospital Management of Respiratory Syncytial Virus Bronchiolitis

Samya Z. Nasr, Peter J. Strouse, Errol I. Soskolne et al. · CHEST Journal · 2001 · 103 citations

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Use of computerized tomography and chest X‐rays in evaluating efficacy of aerosolized recombinant human DNase in cystic fibrosis patients younger than age 5 years: A preliminary study*

Samya Z. Nasr, Lawrence R. Kuhns, Randall W. Brown et al. · Pediatric Pulmonology · 2001 · 91 citations

DNase and atelectasis in non-cystic fibrosis pediatric patients

Tom Hendriks, Matthijs de Hoog, Maarten H. Lequin et al. · Critical Care · 2005 · 84 citations · Full text