Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice

Antidepressant effects of ketamine in depressed patients

Robert Berman, Angela Cappiello, Amit Anand et al. · Biological Psychiatry · 2000 · 3.8K citations

Medicine, Pharmacology, Psychiatry +14

The use of the elevated plus maze as an assay of anxiety-related behavior in rodents

Alicia A. Walf, Cheryl A. Frye · Nature Protocols · 2007 · 3K citations · Full text

Life Sciences, Behavioral Sciences, Neuroscience +11

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Nanxin Li, Boyoung Lee, Rongjian Liu et al. · Science · 2010 · 2.9K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Bita Moghaddam, Barbara W. Adams, Anita Verma et al. · Journal of Neuroscience · 1997 · 1.8K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

Denis J. David, Benjamin A. Samuels, Quentin Rainer et al. · Neuron · 2009 · 1.2K citations · Full text

Medicine, Neuroscience, Pharmacology +14