PubMed · 1975 · 88 citations · 0 references
MedicineMaxillofacial SurgeryAntimicrobial PharmacotherapyAntimicrobial StewardshipInfection PreventionAntibiotic ProphylaxisBone InfectionsFracture ManagementFracture-related InfectionMandibular FracturesTooth FracturesAntibiotic Penetration Into BoneBone Infection EpidemiologyInfection In Mandibular FracturesOral Antibiotic Therapy
The need for antibiotic coverage in compound mandibular fractures was tested in 64 patients with fractures in tooth-bearing areas in a study that began in January 1971 and ended in May 1974. Half of the patients received antibiotic coverage as part of the management of their fractures; the other half did not receive antibiotics. Problems related to infection at a fracture site developed in only 6.25% of patients treated with antibiotics. Infections directly associated with fractures developed in 50.33% of patients who did not receive antibiotic coverage.