Publication | Closed Access
Hamster Ependymomas Produced by Intracerebral Inoculation of a Human Papovavirus (MMV)
48
Citations
0
References
1976
Year
Molecular VirologyHamster Ependymomas ProducedNeurovirologyViral PathogenesisImmunologyPathologyVirologyIntracerebral InoculationSimian Virus 40Newborn HamstersVirus-host InteractionHuman PapovavirusAdult T-cell Leukemia-lymphomaImmunotherapyMedicineViral OncologyAnimal VirusT Antibody
Ependymomas were produced in 3 of 11 newborn hamsters inoculated intracerebrally with a human papovavirus (MMV) isolated from a malignant lymphoma of the brain of a child with Wiskott-Aldrich syndrome. One of the tumors was serially transplanted into weanling hamsters. Cells from the transplanted tumors and from cell cultures derived from these tumors contained an intranuclear "T" antigen that reacted with simian virus 40 T antibody.