Topical fentanyl stimulates healing of ischemic wounds in diabetic rats 局部芬太尼麻醉可以促进糖尿病大鼠缺血性伤口的愈合

Abstract

Topically applied fentanyl promotes closure of ischemic wounds in diabetic rats. Increased angiogenesis, lymphangiogenesis, peripheral nerve regeneration, NO and PDGFR-β signaling are associated with fentanyl-induced tissue remodeling and wound healing.