Pseudoporphyria associated with voriconazole.

Abstract

Pseudoporphyria is a rare photosensitivity that resembles porphyria cutanea tarda clinically but lacks the biochemical derangements in porphyrin metabolism. The majority of cases are induced by ingestion of particular medications. We report a case of pseudoporphyria induced by voriconazole, a second-generation triazole antifungal agent, in a lung transplant recipient. Voriconazole was not discontinued due to medical necessity. The patient's pseudoporphyria was adequately controlled with UVA and UVB protection sunscreen despite continued mild sun exposure.