PubMed · 1980 · 11 citations · 0 references
MedicineImmunologyNeurologyImmunopathologyNeuroimmunologyNeuropathologyAutoimmune Neurological DisordersImmunoglobulin DisordersPeripheral NeuropathiesAutoimmune Peripheral NeuropathiesMyeloma Pathogenesis
Peripheral neuropathies were the presenting feature of an IgA lambda myeloma in a 61-year-old man and a mixed cryoglobulinaemia in a 46-year-old woman. A spectacular improvement in these symptoms followed treatment including large volume plasma exchanges with appropriate chemotherapy. This efficacy of repeated plasmapheresis leads to a discussion of the possible mechanisms of these neuropathies.