Failure of Syndrome-Based Diarrhea Management Guidelines to Detect<i>Shigella</i>Infections in Kenyan Children

Abstract

Reliance on dysentery as a proxy for Shigella results in the majority of Shigella-infected children not being identified for antibiotics. Field-ready rapid diagnostics or updated evidence-based algorithms are urgently needed to identify children with diarrhea most likely to benefit from antibiotic therapy.