Regulators of G Protein Signaling (RGS) Proteins as Drug Targets: Modulating G-Protein-Coupled Receptor (GPCR) Signal Transduction

Abstract

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTRegulators of G Protein Signaling (RGS) Proteins as Drug Targets: Modulating G-Protein-Coupled Receptor (GPCR) Signal TransductionMiniperspectiveDavid L. Roman† and John R. Traynor*‡§View Author Information† Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, 115 S. Grand Avenue, Iowa City, Iowa 52242, United States‡ § ‡Department of Pharmacology and §Substance Abuse Research Center, University of Michigan, Ann Arbor, Michigan 48109, United StatesPhone: 734-647-7479. E-mail: [email protected]Cite this: J. Med. Chem. 2011, 54, 21, 7433–7440Publication Date (Web):September 14, 2011Publication History Received10 December 2010Published online29 September 2011Published inissue 10 November 2011https://pubs.acs.org/doi/10.1021/jm101572nhttps://doi.org/10.1021/jm101572nreview-articleACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views3042Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cell signaling,Monomers,Peptides and proteins,Receptors,Rodent models Get e-Alerts