PubMed · 1958 · 553 citations · 3 references
Life SciencesBiologyGeneticsHuman GeneticsPopulation GeneticsQuantitative GeneticsAnthropometric VariationBiometricsGenetic CorrelationPopulation Genetics InferencePopulation StructurePopulation VariationAnthropometric HeredityBiological Distance AnalysisFst EstimationHuman Population StructurePhenetic AnalysisPhenotypic TraitsPopulation Genetic StructureQuantitative Trait Genetics
Anthropometric measurements (head length, head breadth, bizygomatic diameter, minimum frontal diameter, head circumference, and stature) for 526 adult Jirels are utilized to establish the pattern of phenotypic relationships between seven villages in eastern Nepal. An analytical framework is provided that justifies the interpretation of biological distances as minimum genetic distances. Using this approach, estimates of the minimum pairwise genetic distances between villages and the minimum FST for the population are derived from the purely phenotypic data. The FST obtained in this way is consistent with results obtained from other data available for this population, confirming the utility of phenetic analysis of quantitative traits for elucidating genetic structure.
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EVOLUTION IN MENDELIAN POPULATIONS
Sewall Wright · Genetics · 1931 · 9.1K citations · Full text
The Effect of Variation of Fitness
J. B. S. Haldane · The American Naturalist · 1937 · 671 citations