The Medical Journal of Australia · 1980 · 12 citations · 11 references
PharmacyPharmacologyPharmacotherapyClinical PharmacologyHepatic PharmacotherapyPoisoning ManagementCholestatic Liver InjuryHepatic ToxicityHepatotoxicity ManagementHepatotoxicity MechanismsN-acetylcysteine TherapyPharmacokinetics In Liver DiseaseHepatocellular Liver InjuryLiver Toxicity AssessmentN-acetylcysteine Mechanism Of ActionN-acetylcysteine PharmacologyParacetamol Toxicity
Intravenously administered N-acetylcysteine was used to treat 11 patients at risk of hepatic damage from paracetamol poisoning. Complete protection against liver failure was seen in all cases without any adverse effects. The efficacy and safety of intravenously administered N-acetylcysteine make it the treatment of choice in paracetamol poisoning.
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Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.
L. F. Prescott, R. N. Illingworth, Julia Critchley et al. · BMJ · 1979 · 665 citations · Full text
TREATMENT OF PARACETAMOL (ACETAMINOPHEN) POISONING WITH N-ACETYLCYSTEINE
L. F. Prescott, Anna Ballantyne, A. T. Proudfoot et al. · The Lancet · 1977 · 462 citations
CYSTEAMINE, METHIONINE, AND PENICILLAMINE IN THE TREATMENT OF PARACETAMOL POISONING
L. F. Prescott, George R. Sutherland, Jay J. Park et al. · The Lancet · 1976 · 208 citations