PubMed · 2012 · 11 citations · 0 references
Life SciencesCell BiologyMolecular BiologyAgingCell DivisionGene ExpressionCellular AgingRna StructureAgeingCentrosome BiologyCentrosome FunctionCentrosome Organization
The recent discovery of a new class of RNA in a centrosome may be an indirect evidence of the centrosomal hypothesis of cellular ageing and differentiation. The presence of a reverse transcriptase domain in this class of RNA, together with its specificity to this organelle, makes the centrosome a place of information memorizing and reproduction. This feature of centrosome is one of the main points of centrosomal hypothesis of cell aging and differentiation.