RheumatologyApparent Secondary AmyloidosisPathologyDegenerative DiseaseHla B27Protein MisfoldingDermatologySclerodermaMedicineSecondary AmyloidosisNeuropathology
A patient with a 27-year-history of chronic relapsing Reiter's syndrome who developed secondary amyloidosis is described. While there are only 2 reports of this association in the English literature, additional cases are suggested in the light of our present concepts. The patient represents the only case of clinically apparent secondary amyloidosis among 158 patients with HLA B27 associated arthropathies currently followed at our institution. Our patient's amyloidosis was treated for nearly 1 year with colchicine without response.