PubMed · 1997 · 28 citations · 0 references
Life SciencesMolecular BiologyMolecular GeneticsGenomicsMolecular VirologyVirologyEncephalitisTick BiologyTick-borne DiseasesVector-borne TransmissionVector-borne ZoonosesViral InfectionsArboviral EncephalitisTick GenomicsTick Pathogen TransmissionTick-borne Pathogen TransmissionTick-borne PathogensTick-borne TransmissionTick-borne Viral ZoonosesViral Encephalitis
Tick-borne encephalitis (TBE) virus is an important human pathogen belonging to the genus Flavivirus within the family Flaviviridae. The genome of the TBE virus is a single-stranded RNA (ssRNA) molecule of positive polarity encoding all the viral proteins within a single open reading frame (ORF). TBE virus shares common physical and genetic characteristic of the flavivirus genus. Two subtypes of the TBE virus have been described: (1) European, endemic in many parts of Europe and transmitted by Ixodes ricinus ticks, and (2) Far Eastern (Russian spring summer encephalitis (RSSE) virus), endemic in Far East and transmitted by Ixodes persulcatus ticks.