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Distribution of glutathione peroxidase activity and selenium in the blood of dairy cows.
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1979
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NutritionEducationLivestock HealthRedox BiologyOxidative StressDairy CowsHematologyFeed AdditiveToxicologyAnimal ProductionEnzyme ActivityAnimal PhysiologyBiochemistrySelenium DeficiencyAnimal NutritionGlutathione PeroxidaseGlutathione Peroxidase ActivityWhole Blood SeleniumAnimal SciencePhysiologyAnimal HealthMetabolismMedicine
The distribution of glutathione peroxidase (GSH-Px) activity and selenium concentrations among several components in the blood of dairy cows was examined. Approximately 98% of the GSH-Px activity in peripheral blood was associated with the erythrocytes when enzyme activity was expressed as units per milliliter of blood. The GSH-Px activity expressed per cell was approximately fourfold greater for peripheral leukocytes than for erythrocytes. The cellular component contained a greater proportion (approx 73%) of whole blood selenium than did the plasma. A positive linear relationship (r = 0.958) between blood GSH-Px activity and blood selenium concentrations was found in dairy cattle under practical field conditions.