TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells. - Concepedia

Concepedia

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TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells.

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2014

Year

Xiangjun Tang, Junti Lu, Hanjun Tu, Kuan-Ming Huang, Rui Fu, Gang Cao, Min Huang, Long-Hai Cheng, Long‐Jun Dai, Li Zhang

Abstract

Mesenchymal stem cells were very well tolerant to the transfection of TRAIL-bearing vectors. The cytotoxic effects of TRAIL-engineered MSCs on C6 cells indicates the therapeutic potential of this strategy for treatment of glioblastoma patients.