MedicineGynecologyObstetricsAssisted Reproductive TechnologiesEmbryo TransferReproductive MedicineEmbryo Transfer TechniquesFemale InfertilityOocyte RetrievalOvarian FunctionPregnancyUterine FibroidsDonor Oocyte SelectionDonor OocytesEmbryo Transfer Outcome AssessmentIntramural FibroidsMiscarriage RatePregnancy Outcome AssessmentSubserosal FibroidsUterine Sonography
PURPOSE: To evaluate the effect of intramural or subserosal fibroids in the uterine fundus or corpus on pregnancy outcome following transfer of embryos formed from donated oocytes methods. METHODS: Leiomyomata were measured in three dimensions by transvaginal sonography. Scanning was performed in two planes (sagittal and coronal) at the level of maximal width. The location was categorized by depth in the uterus. RESULTS: There was no difference in pregnancy rates in those with or without fibroids. However, there was a significantly higher miscarriage rate in the former group. CONCLUSION: Women with fibroids are generally older. Thus conclusions about the effect on miscarriage rates are complicated by the effect of the aging oocyte on miscarriages. This study eliminated the oocyte factor by using only younger donated oocytes.