Differences in the autonomic reactivity pattern to psychological load in patients with hypertension and rheumatic diseases.

Abstract

As a ground-based reference study to a space experiment, a complex psychophysiological test battery (heart rate, blood pressure, skin conductance, finger temperature, forearm electromyogram during psychological loading task solving) was developed and first applied on two cohorts of subjects with different blood pressure levels at rest (53 hypertensive patients, and 30 normal controls). The data describing autonomic reactivity could be differentiated by cluster analysis into four Autonomic Outlet Types (AOT). The method was subsequently applied to 20 patients with systemic Lupus erythematosus and 13 subjects with rheumatoid arthritis to work out a discriminant function for classifying and testing it's validity. The AOT classification of all subjects showed a significant correlation with the different types of diseases.