PubMed · 2015 · 49 citations · 0 references
Life SciencesGeneticsOncologyCancer GeneticsGenetic CounselingHuman GeneticsBreast Cancer Risk AssessmentCancer RiskGenetic Counseling In FamiliesGenetic Risk AssessmentGermline Cancer PredispositionGermline Cancer SusceptibilityBrca MutationsBreast Cancer HistoryBreast Risk AssessmentFamilial Breast CancerFamily History-based ScreeningGenetic TestingHereditary Breast Cancer Risk Assessment
L.M. is a 37-year-old nonsmoking woman who is not taking any medications and has no significant past medical problems. Three of her female relatives have a history of breast cancer: her mother (diagnosed at 49 years of age, before menopause), her paternal grandmother (diagnosed at 72 years of age), and her maternal aunt (recently diagnosed at 39 years of age). L.M. is concerned that breast cancer runs in her family, and is interested in genetic testing for breast cancer.