Gadolinium DTPA (an NMR proton imaging contrast agent): chemical structure, paramagnetic properties and pharmacokinetics.

Edward J. Goldstein, K. Burnett, John R. Hansell, J Casaia, José Dizon, B Farrar, Daphna Y. Gelblum, Gerald Wolf

PubMed · 1984 · 39 citations · 0 references

Concepts

Abstract

The structure, chemical properties, metabolic pathway and NMR contrast efficacy of Gadolinium-DTPA are described. This reagent has great promise as a contrast agent in NMR proton imaging, and clinical trials have been initiated in England and Germany.