[Evaluation of the Vidas system for the serological diagnosis of toxoplasmosis].

Abstract

The recent immuno-analysis system Vidas (bioMérieux) for the serological diagnosis of toxoplasmosis was compared to the Abbott Toxo EIA system, taking the indirect immunofluorescence assay (IFA) as reference for immunoglobulin G and the immunosorbent agglutination assay (ISAGA) for immunoglobulin M. Five hundred and ninety-four individual sera and 15 seroconversions or recent infections (39 sera) were studied. Sensitivity and specificity of the Vidas system were respectively 99.7% and 99.4% for IgG, and 100% and 97% for IgM. During primary toxoplasmia infection, the Vidas system allows very early detection of the appearance of IgM and IgG. The Vidas Toxo IgG is more sensitive than the Abbott G EIA. For IgM, the Vidas Toxo M is less specific but much more sensitive than the Abbott M EIA.