PubMed · 2001 · 32 citations · 0 references
Low ToxicityBehavioral StudyNeurotransmitterSocial SciencesNeurologyNeurochemistryMolecular NeuroscienceBehavioral NeuroscienceBehavioural PharmacologyNeuropharmacologySpontaneous Locomotor ActivityNervous SystemPharmacologyNeurophysiologyNeuroscienceBiological PsychiatryCentral Nervous SystemMolecular NeurobiologyNew Monoterpene HomologuesMedicine
This behavioral study in mice showed that the monoterpene homologues of GABA (SL-1, SL-2 and SL-3), characterized by low toxicity, induced an increase in spontaneous locomotor activity (SL-2 and SL-3). Moreover, SL-3 shortened hexobarbital-induced sleeping time, and SL-1 showed anticonvulsant activity in pentetrazole-induced seizures.