Major Superficial White Matter Abnormalities in Huntington's Disease

Owen R. Phillips, Shantanu H. Joshi, Ferdinando Squitieri, Cristina Sánchez‐Castañeda, Katherine L. Narr, David W. Shattuck, Carlo Caltagirone, Umberto Sabatini, Margherita Di Paola

Frontiers in Neuroscience · 2016 · 77 citations · 35 references

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Abstract

This study showed broad abnormalities in superficial white matter even before symptoms are present in Huntington's disease. Since, the superficial white matter has a unique microstructure and function these abnormalities suggest it plays an important role in the disease.

References

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