PubMed · 1989 · 16 citations · 0 references
PharmacyPharmacotherapyPsychiatryClinical PharmacologyPsychiatric PharmacotherapyPsychopharmacologyAntidepressant PharmacologyAntidepressant PharmacotherapyAntidepressant TherapyDepression AssessmentDepression ManagementDepression PharmacotherapyAntidepressant EfficacyAntidepressant MedicationsAntidepressant ResponseAntidepressant SafetyAntidepressant TolerabilityDepressive Symptom AssessmentDouble-blind TrialsTricyclic Antidepressant Therapy
A double-blind clinical trial was undertaken to evaluate clinical efficacy and safety of fluoxetine in comparison with the standard tricyclic antidepressant, imipramine, in the treatment of depressive illness. The opportunity was taken to compare the relationship of some standard measures of depressive illness, two observer based--Hamilton Depression Rating Scale and the Montgomery-Asberg Depression Rating Scale (Montgomery and Asberg, 1979)--and a self-rating scale--Levine Pilowsky Depression questionnaire (Pilowsky et al., 1969).