PubMed · 1982 · 59 citations · 0 references
MedicineImmunologyObstetricsAutoimmunityFertilityHigh-risk PregnancyConnective Tissue DiseasesConnective Tissue DisordersPregnancyPregnancy Loss PathologyReproductive AutoimmunitySystemic Lupus ErythematosusAutoimmune Pregnancy ComplicationsConnective Tissue Disease PathologyFetal MortalityMaternal Autoimmune DiseasePregnancy In LupusPregnancy MorbiditySystemic Lupus Erythematosus Associations
The risk of pregnancy was evaluated in 31 patients with mixed connective tissue disease (MCTD), 31 patients with systemic lupus erythematosus (SLE) and 51 controls. The fertility rates in MCTD and SLE were unaltered by disease; however, parity was decreased and fetal wastage was increased both before and even more so after onset. It is our observation that pregnancy carries the same risks in MCTD as it does in SLE.