Annals of Clinical and Translational Neurology · 2016 · 30 citations · 10 references
MedicineNeurologySurgeryPain ManagementPain MedicinePeripheral Nerve SurgeryBrachial Plexus SurgeryHand RehabilitationNerve ReconstructionNerve RegenerationNerve RepairPhantom Limb PainBrachial Plexus RehabilitationCortical ReorganizationInterpositional Nerve GraftingNerve Graft ReconstructionPhantom Limb Pain MechanismsPhantom Limb Pain ModulationPhantom Limb Pain SurgerySensory Remapping
Following left brachial plexus avulsion, a 20-year-old man had phantom limb pain and remapping of sensation from his paralyzed hand onto his face. Mirror therapy (15 min daily, 5 days/week) led immediately to good movement of the phantom limb with decreased pain. Within 2 weeks following nerve graft surgery, remapping of hand sensation onto the face disappeared along with resolution of phantom limb pain. Mirror therapy coupled with nerve grafting may relieve phantom limb pain due to brachial plexus avulsion and reverse hand-to-face remapping, suggesting that both peripheral and central mechanisms mediate development of phantom limb pain and cortical reorganization/neuroplasticity after brachial plexus avulsion.
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Phantom movements and pain An fMRI study in upper limb amputees
Martín Lotze · Brain · 2001 · 444 citations · Full text
Phantom Limbs and Neural Plasticity
V. S. Ramachandran, Diane Rogers-Ramachandran · Archives of Neurology · 2000 · 239 citations