[The association of single nucleotide polymorphism of slow delayed rectifier K+ channel genes with atrial fibrillation in Han nationality Chinese]. - Concepedia

Concepedia

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[The association of single nucleotide polymorphism of slow delayed rectifier K+ channel genes with atrial fibrillation in Han nationality Chinese].

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References

2005

Year

Zhi Zeng, Jie Pu, Tan Chen, Si Teng, Jian hong Chen, Shaoyong Su, Xiao Zhou, Shu Zhang, Yi shi Li, Fang zheng Wang,

Abstract

None of the SNPs of KCNQ1 P448R, KCNQ1 R519H, KCNQ1 G643S, KCNE1 G38S and KCNE1 D85N was associated with atrial fibrillation phenotype, but KCNE4 E145D may relation to atrial fibrillation. The effect of KCNE4 E145D variation on the function of I(Ks) channel is to be determined.