Simvastatin reduces interleukin-1β secretion by peripheral blood mononuclear cells in patients with essential hypertension

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

Anders Olsson, John J.V. McMurray, G Thorgeirsson et al. · The Lancet · 1994 · 8.5K citations

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The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

Frank M. Sacks, Marc A. Pfeffer, Lemuel A. Moyé et al. · New England Journal of Medicine · 1996 · 7.5K citations · Full text

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Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

James Shepherd, Stuart M. Cobbe, Ian Ford et al. · New England Journal of Medicine · 1995 · 7.5K citations · Full text

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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

The Lancet · 2002 · 7K citations

Medicine, Cardiology, Pharmacotherapy +13

Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

New England Journal of Medicine · 1998 · 5.3K citations · Full text

Medicine, Cardiology, Pharmacology +15