Initiating Sacubitril/Valsartan (LCZ696) in Heart Failure: Results of TITRATION, a Double-Blind, Randomized Comparison of Two Uptitration Regimens - Concepedia

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Initiating Sacubitril/Valsartan (LCZ696) in Heart Failure: Results of TITRATION, a Double-Blind, Randomized Comparison of Two Uptitration Regimens

DOI Full Paper Access

233

Citations

12

References

2016

Year

Michele Senni, John J.V. McMurray, Rolf Wachter, Hugh McIntyre, Antonio Reyes, Ivan Majerčák, Péter Andréka, Nina S Shehova-Yankova, Inder S. Anand, Harinder Gogia,

European Journal of Heart Failure

Abstract

Initiation/uptitration of sacubitril/valsartan from 50 to 200 mg twice daily over 3 or 6 weeks had a tolerability profile in line with other HF treatments. More gradual initiation/uptitration maximized attainment of target dose in the low-dose ACEI/ARB group.

References

	Year	Citations

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