Concepedia

Publication | Open Access

GSK3ß‐dependent dysregulation of neurodevelopment in SPG11‐patient induced pluripotent stem cell model

DOIFull Paper Access

45

Citations

35

References

2016

Year

Himanshu Mishra, Iryna Prots, Steven Havlicek, Zacharias Kohl, Francesc Pérez‐Brangulí, Tom Boerstler, Lukas Anneser, Georgia Minakaki, Holger Wend, Martin Hampl,
Annals of Neurology

Abstract

This iPSC-derived NPC model provides the first evidence for an early neurodevelopmental phenotype in SPG11, with GSK3ß as a potential novel target to reverse the disease phenotype. Ann Neurol 2016;79:826-840.

References

YearCitations

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