A computational approach to early sepsis detection

PhysioBank, PhysioToolkit, and PhysioNet

Ary L. Goldberger, Luı́s A. Nunes Amaral, Leon Glass et al. · Circulation · 2000 · 14.5K citations · Full text

Engineering, Biomedical Engineering, Physiology +15

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.8K citations · Full text

Veterinary Medicine, Immunology, Pharmacotherapy +15

Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey Lidicker et al. · Critical Care Medicine · 2001 · 8.6K citations

Veterinary Medicine, Infectious Diseases, Internal Medicine +16

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

Anand Kumar, Daniel Roberts, Kenneth E. Wood et al. · Critical Care Medicine · 2006 · 6.1K citations

Veterinary Medicine, Infectious Diseases, Antimicrobial Pharmacotherapy +13

A Randomized Trial of Protocol-Based Care for Early Septic Shock

New England Journal of Medicine · 2014 · 2.4K citations · Full text

Veterinary Medicine, Critical Care Nursing, Sepsis +5