Concepedia

Publication | Open Access

Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma

DOIFull Paper Access

290

Citations

34

References

2016

Year

Toni K. Choueiri, Mayer Fishman, Bernard Escudier, David F. McDermott, Charles G. Drake, Harriet M. Kluger, Walter M. Stadler, José Luis Perez‐Gracia, Douglas G. McNeel, Brendan D. Curti,
Clinical Cancer Research

Abstract

Immunomodulatory effects of PD-1 inhibition were demonstrated through multiple lines of evidence across nivolumab doses. Biomarker changes from baseline reflect nivolumab pharmacodynamics in the tumor microenvironment. These data may inform potential combinations. Clin Cancer Res; 22(22); 5461-71. ©2016 AACR.

References

YearCitations

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