Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies

Baijun Kou, Wanzhi Huang, Frederick H. Neill, Timothy Palzkill, Mary K. Estes, Robert L. Atmar

Journal of Clinical Microbiology · 2015 · 11 citations · 9 references

DOIFull text

Open access

Concepts

Abstract

The performance of a norovirus antigen detection assay was assessed using monoclonal antibody NV23 and single-chain antibody HJT-R3-A9 to identify both virus-like particles and virus-containing fecal samples. The detection of 25 different norovirus genotypes as recombinant virus-like particles or in clinical samples was dependent on virus or antigen concentration.

References

9