[Effect of melatonin on release of beta-endorphin, norepinephrine and 5-hydroxytryptamine in rat brain].

Abstract

Melatonin may promote the release of beta-Ep in brain, which may be one of the mechanisms of the analgesic action of melatonin. The analgesic action of melatonin may not be related to the release of NE and 5-HT in the PAG or the hypothalamus.