Concepedia

Infliximab therapy in pulmonary fibrosis associated with collagen vascular disease.

M Mamoulaki, Katerina Malagari, H D Kritikos, Demosthenes Bouros, Nikolaos M. Siafakas, DT Boumpas

PubMed · 2007 · 91 citations · 15 references

Abstract

This study suggests that inhibition of TNF-alpha with infliximab may stabilize the progression of pulmonary fibrosis associated with CVD. Prospective, controlled trials are necessary to determine the efficacy of infliximab in pulmonary fibrosis associated CVD.

References

15

Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis

Peter E. Lipsky, Désirée van der Heijde, E. William St. Clair et al. · New England Journal of Medicine · 2000 · 3K citations · Full text

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management

Gert Van Assche, James O. Lindsay, Marc Lémann et al. · Journal of Crohn s and Colitis · 2010 · 1.5K citations

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Histopathologic Subsets of Fibrosing Alveolitis in Patients with Systemic Sclerosis and Their Relationship to Outcome

Demosthenes Bouros, Athol U. Wells, Andrew G. Nicholson et al. · American Journal of Respiratory and Critical Care Medicine · 2002 · 809 citations

TNF-α-mediated lung cytokine networking and eosinophil recruitment in pulmonary fibrosis

Kai Zhang, Mehrnaz Gharaee‐Kermani, Bridget McGarry et al. · The Journal of Immunology · 1997 · 171 citations · Full text

Tumor necrosis factor mediates experimental pulmonary edema by ICAM-1 and CD18-dependent mechanisms.

S K Lo, Jeffrey I. Everitt, Jiang Gu et al. · Journal of Clinical Investigation · 1992 · 168 citations · Full text

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