Blocking transforming growth factor-beta receptor signaling down-regulates transforming growth factor-beta1 autoproduction in keloid fibroblasts. - Concepedia

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Blocking transforming growth factor-beta receptor signaling down-regulates transforming growth factor-beta1 autoproduction in keloid fibroblasts.

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2002

Year

Wei Liu, Ze-hao Cai, Danru Wang, Xiaoli Wu, Lei Cui, Qingxin Shang, Yunliang Qian, Yilin Cao

Abstract

TGF-beta1 autoproduction was observed in keloid fibroblasts. Over-expression of the truncated TGFbeta receptor II decreased TGF-beta1 autoproduction via blocking TGF-beta receptor signaling.