The efficacy of Cordyceps militaris capsules in treatment of chronic bronchitis in comparison with Jinshuibao capsules

Abstract

Objective: To evaluate the efficacy and safety of Cordyceps militaris capsules in treatment of chronic bronchitis. Methods:The multi-centers,randomized,single blind,and positive controlled study was conducted in 425 patients with chronic bronchitis. They were divided to receive Cordyceps militaris capsules in a dose of 1g tid for 2 months ( n = 315) or Jinshuibao capsule in a dose of 1g tid for 2 months ( n = 110). Results:The symptom of cough,sputum,and wheeze as well as lung function, chest X ray syndrome and comprehensive efficacy in the active group were significantly improved compared with control group (P 0.01). No significant difference in blood routine examination, liver and renal functions, ECG and others between 2 groups were observed (P0. 1). Conclusion : Cordyceps militaris capsules are effective in treatment of chronic bronchitis.