A Mitochondrion‐Specific Photoactivatable Fluorescence Turn‐On AIE‐Based Bioprobe for Localization Super‐Resolution Microscope

Abstract

A novel mitochondrion-specific photo-activatable fluorescence turn-on bioprobe, named as o-TPE-ON+, is designed and readily prepared, operating through a new photoactivatable mechanism of photocyclodehydrogenation. This bioprobe exhibits unique photoactivation behavior in cells, and is applied to super-resolution imaging of mitochondrion and its dynamic investigation in both fixed and live cells under physiological conditions without any external additives.