Bafetinib (INNO-406) reverses multidrug resistance by inhibiting the efflux function of ABCB1 and ABCG2 transporters

ZINC: A Free Tool to Discover Chemistry for Biology

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Molecular Docking, Ligand Discovery, Small Custom Subsets +13

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

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Drug Target, Glycobiology, P-glycoprotein Reveals +19

Role of the breast cancer resistance protein (ABCG2) in drug transport

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Tumor Biology, Breast Oncology, Biochemistry +9

Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity

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Abcg2 Gene, Genetics, Antagonist Specificity +19

Refined structures of mouse P‐glycoprotein

Jingzhi Li, Kimberly Jaimes, Stephen G. Aller · Protein Science · 2013 · 344 citations · Full text

Protein Assembly, Glycobiology, Molecular Biology +20