Evaluation of methanolic bark extract of Tecoma stans Linn, for wound healing in albino rats.

Abstract

Received on 10-08-2010 Accepted on 26-08-2010 The different extracts of the bark of Tecoma stans Linn. (Bignoniaceae) was evaluated for its wound healing potential in two different types of wound models in albino rats viz., incision and excision. The different extracts of Tecoma stans are obtained by successive soxhlet extraction with petroleum ether, chloroform and methanol. The methanolic extract showed significant increase in wound contraction and formation of scar in excision wound model. The extract showed significant increase in the breaking strength of resutured incision wound as compared to control group(p<0.05). The result of the present study indicate that methanolic extract of Tecoma stans bark has more significant wound healing property than the petroleum ether and chloroform extracts in excision and incision wound model. The presence of phytoconstituents like phytosterols, triterpene, glycosides, phenols, flavonoids, saponins, and tannins either individually or combined together may exhibit the synergistic effect towards healing of wounds. The wound healing property of Tecoma stans has been attributed to its antimicrobial effects. From the result obtained, it may be concluded that the methanolic extract has significant wound healing property.