Concepedia

Replacement of an NH<sub>3</sub>by an Iminoether in Transplatin Makes an Antitumor Drug from an Inactive Compound

Marc Leng, Daniel Locker, Marie‐Josèphe Giraud‐Panis, Annie Schwartz, Francesco P. Intini, Giovanni Natile, Claudio Pisano, Angelina Boccarelli, Domenico Giordano, Mauro Coluccia

Molecular Pharmacology · 2000 · 51 citations · 33 references

DOI

Concepts

References

33

DNA bending at adenine · thymine tracts

Hyeon‐Sook Koo, Hen‐Ming Wu, Donald M. Crothers · Nature · 1986 · 1K citations

, , +12

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

Patricia M. Takahara, Amy C. Rosenzweig, Christin Frederick et al. · Nature · 1995 · 767 citations

, , +15

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

Uta‐Maria Ohndorf, Mark A. Rould, Qing He et al. · Nature · 1999 · 562 citations

, , +5

Platinum-195 NMR kinetic and mechanistic studies of cis- and trans-diamminedichloroplatinum(II) binding to DNA

Daniel P. Bancroft, Christopher A. Lepre, Stephen J. Lippard · Journal of the American Chemical Society · 1990 · 478 citations

, , +8

Intrinsically bent DNA.

Donald M. Crothers, Tali E. Haran, James G. Nadeau · Journal of Biological Chemistry · 1990 · 428 citations · Full text

, , +11