Aluminium(III) Chloride‐Catalyzed Three‐Component Condensation of Aromatic Aldehydes, Nitroalkanes and Sodium Azide for the Synthesis of 4‐Aryl‐<i>NH</i>‐1,2,3‐triazoles

Abstract

Abstract An aluminium(III) chloride‐catalyzed three‐component reaction of aromatic aldehydes, nitroalkanes, and sodium azide has been developed; this reaction sequence can be applied to a broad substrate scope and affords the corresponding 4‐aryl‐ NH ‐1,2,3‐triazoles in good to excellent yields. The milder reaction conditions and easier operation make this AlCl 3 ‐catalyzed protocol more advantageous for the synthesis of 4‐aryl‐ NH ‐1,2,3‐triazoles. magnified image