Immunohistochemical expression of <scp>DNA</scp> methyltransferases 1, 3a, and 3b in actinic cheilitis and lip squamous cell carcinomas

Abstract

The results suggested that DNMT 3a could play a key role in the methylation process of initial steps of UV carcinogenesis present in AC while DNMT 3b could be responsible for de novo methylation in already established lip cancer.