Note on the presence of a new serum protein in the blood of various animals

Abstract

THE observation that horse serum albumin can be separated into fractions of widely different properties led to the preparation of two proteins, namely crystalbumin, which is carbohydrate-free, and seroglycoid, a new serum protein, to which is due the greater part of the polysaccharide content of horse serum albumin Some 10-20% of horse serum albumin consists of seroglycoid which, when isolated, has very characteristic properties, not being heat-coagulable or precipitable by 2 % trichloroacetic acid. The present experiments were conducted with a view to determining whether horse serum is unique in this respect or whether proteins similar to seroglycoid occur in the blood serum of other animals.