Allergic contact dermatitis caused by resorcinol and sodium dehydroacetate in a patient with leg ulcers

Abstract

Resorcinol, also known as resorcin (1,3-dihydroxybenzene;
\nCAS no. 108-46-3), is an important ingredient
\nof Castellani’s paint solution, an antifungal preparation
\nthat is commonly used in daily dermatological clinical
\npractice. Apart from its use in hair dyes, resorcinol is
\nalso used in several other topical preparations, because
\nof its antipruritic, keratolytic and antimycotic properties.
\nSodium dehydroacetate (CAS no. 4418-26-2) is a preservative
\nused in several topical products, in particular for
\nthe treatment of ulcers, and has already been reported
\nto be sensitizing. We describe a case of allergic
\ncontact dermatitis caused by resorcinol and sodium
\ndehydroacetate in a patient affected by leg ulcers.