Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With<i>BAP1</i>Mutations

Abstract

The prevalence of mutations in the UM related genes is not different in polyploid UM compared with diploid UM. Moreover, similar to patients with diploid UM, BAP1 mutation is the most significant prognostic predictor of metastasis in patients with polyploid UM.