THE SENSITIVITY OF THE NEURAMINOSIDIC LINKAGE IN MUCOSUBSTANCES TOWARDS ACID AND TOWARDS NEURAMINIDASE

Abstract

other moving faster (mobility 0.52). This suggested incomplete cleavage at the second stage, resulting in the production of CPOb2 together with CPO13 at the third stage. Cleavage appeared to be com- plete at all subsequent stages, although two peptides were always obtained, owing to the incomplete cleavage of the second stage. The DNS-CPO04 (mobility 0.56) and DNS-CPO,5 (mobility 0 78) were obtained in reasonable yield. The DNS- CPOf6 was identified as a very weak band (mobility 0 94), moving in the tail of the dimethylaminonaphthalenesulphonic acid band. Subsequent stages were unsuccessful, since labelling was inhibited by the presence of an accumulation of oxidized pyridine products.